Folate intake, markers of folate status and oral clefts: is the evidence converging?

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Folate intake, markers of folate status and oral clefts: is the evidence converging?

BACKGROUND The ability of folic acid in the periconceptional period to prevent the occurrence of neural tube defects has stimulated tremendous interest in its effects on other health outcomes. Its possible effect on oral clefts has generated considerable debate. The purpose of this systematic review and meta-analysis was to assemble evidence on the role of folate in the aetiology of cleft lip w...

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ژورنال

عنوان ژورنال: International Journal of Epidemiology

سال: 2008

ISSN: 0300-5771,1464-3685

DOI: 10.1093/ije/dyn098